Heat the oven to 375°F and grease a 9-inch oven-safe skillet.
In the skillet, stir together the cream of chicken soup, milk, garlic powder, poultry seasoning, shredded chicken, and frozen vegetables until everything is evenly combined.
Arrange the quartered biscuit pieces across the top of the filling.
Bake for 20 minutes.
While it bakes, whisk together the melted butter, honey, and Dijon mustard until smooth.
Remove the skillet from the oven and brush the biscuits generously with the honey Dijon butter. Lightly tent the skillet with foil and return it to the oven.
Bake another 10 to 15 minutes, until the biscuits are golden and cooked through and the filling is bubbling around the edges.
Let the skillet rest for 5 minutes before serving so the filling thickens slightly.